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Article

Prevalence of copy-number neutral LOH in glioblastomas revealed by genomewide analysis of laser-microdissected tissues.

Neuro-oncology - 1 Dec 2008

Kuga Daisuke, Mizoguchi Masahiro, Guan Yanlei, Hata Nobuhiro, Yoshimoto Koji, Shono Tadahisa, Suzuki Satoshi O, Kukita Yoji, Tahira Tomoko, Nagata Shinji, Sasaki Tomio, Hayashi Kenshi

Abstract excerpt

We have employed a laser-capture microdissection technique and single-nucleotide polymorphism arrays to characterize genomic alterations associated with the development of glioblastoma multiforme (GBM). Combined analysis of loss of heterozygosity (LOH) and copy number revealed that more than half...

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Identifiers

PMID: 18697953
DOI: 10.1215/15228517-2008-064
PMCID: PMC2719013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18697953-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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