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Article

Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma.

Journal of the National Cancer Institute - 20 Aug 2008

Yang Hwai-I, Yeh Shiou-Hwei, Chen Pei-Jer, Iloeje Uchenna H, Jen Chin-Lan, Su Jun, Wang Li-Yu, Lu Sheng-Nan, You San-Lin, Chen Ding-Shinn, Liaw Yun-Fan, Chen Chien-Jen

Abstract excerpt

BACKGROUND: The risk of hepatocellular carcinoma (HCC) increases with increasing level of hepatitis B virus (HBV) in serum (viral load). However, it is unclear whether genetic characteristics of HBV, including HBV genotype and specific genetic mutations, contribute to the risk of HCC. We examined the HCC risk associated with HBV genotypes and common variants in the precore and basal core promoter (BCP) regions....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18695135
DOI: 10.1093/jnci/djn243
PMCID: PMC2518166

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Source receipt: pubmed, retrieved 7 Sept 2026.

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