Article
Hepatitis B virus genotype and DNA level and hepatocellular carcinoma: a prospective study in men.
Journal of the National Cancer Institute - 16 Feb 2005
Yu Ming-Whei, Yeh Shiou-Hwei, Chen Pei-Jer, Liaw Yun-Fan, Lin Chih-Lin, Liu Chun-Jen, Shih Wei-Liang, Kao Jia-Horng, Chen Ding-Shinn, Chen Chien-Jen
Abstract excerpt
BACKGROUND: Although chronic infection with hepatitis B virus (HBV) has been established as a cause of hepatocellular carcinoma (HCC), the roles of viral load and HBV genotype remain unclear. METHODS: From 1988 through 1992, baseline blood samples were collected from 4841 Taiwanese men who were HBV carriers but had not been diagnosed with HCC. We used real-time polymerase chain reaction assays of plasma DNA...
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