Article
The identification of senescence-specific genes during the induction of senescence in prostate cancer cells.
Neoplasia (New York, N.Y.) - 1 Sept 2005
Schwarze Steven R, Fu Vivian X, Desotelle Joshua A, Kenowski Michelle L, Jarrard David F
Abstract excerpt
Classic mechanisms of tumor response to chemotherapy include apoptosis and mitotic catastrophe. Recent studies have suggested that cellular senescence, a terminal proliferation arrest seen in vitro, may be invoked during the exposure of cancer cells to chemotherapeutic agents. To identify markers...
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