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Article

A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients

21 Sept 2016

Abstract excerpt

BACKGROUND: Dexamethasone is reported to induce both tumor-suppressive and tumor-promoting effects. The purpose of this study was to identify the genomic impact of dexamethasone in glioblastoma stem cell (GSC) lines and its prognostic value; furthermore, to identify drugs that can counter these side effects of dexamethasone exposure. METHODS: We utilized 3 independent GSC lines with tumorigenic potential for this...

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PMID: 27653222
DOI: 10.1097/ana.0000000000000368

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