Article
Prioritizing Disease Genes by Analysis of Common Elements (PDG-ACE).
AMIA ... Annual Symposium proceedings. AMIA Symposium - 11 Oct 2007
McEachin Richard C, Keller Benjamin J, Zandi Peter P, Almani Mohsen, McInnis Melvin G
Abstract excerpt
Complex diseases are characterized by multiple genetic and environmental influences on disease susceptibility. Since the multiple genetic influences converge on a single phenotype, some commonality may be evident among genes that influence the disease. We exploit this potential commonality among candidate disease genes to prioritize genes for further analysis and to pose novel, statistically significant,...
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