Article
Visualization of CYP2D6 genotype to phenotype correlation in Korean.
AMIA ... Annual Symposium proceedings. AMIA Symposium - 11 Oct 2007
Kim Eun-Young, Jung Hyun-Ju, Lee Sang-Seop, Shon Ji-Hong, Shin Sang-Goo, Shin Jae-Gook
Abstract excerpt
Cytochrome P450 2D6 (CYP2D6) shows high extent of genotypic and phenotypic polymorphism, which causes inter-individual variation in drug disposition of many therapeutic drugs. Genotype and phenotype of CYP2D6 were determined in 130 Koreans. To visualize the genotype-to-phenotype correlation at a glance, a colored map based on CYP2D6 phenotype was created using two cluster algorithms and annotated for CYP2D6...
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