Article
LPIN1 genetic variation is associated with rosiglitazone response in type 2 diabetic patients.
Molecular genetics and metabolism - 1 Jan 2000
Kang Eun Seok, Park Se Eun, Han Seung Jin, Kim So Hun, Nam Chung Mo, Ahn Chul Woo, Cha Bong Soo, Kim Kyung Sub, Lee Hyun Chul
Abstract excerpt
Lipin1 protein, a product of the LPIN1 gene, is required for normal adipose tissue development and metabolism. Lipin1 deficiency results in immature adipocyte development in cases of mouse fatty liver dystrophy and human lipodystrophy. Recently, pioglitazone has been reported to increase human ad...
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