Article
Effects of ABCA1 variants on rosiglitazone monotherapy in newly diagnosed type 2 diabetes patients.
Acta pharmacologica Sinica - 1 Feb 2008
Wang Jie, Bao Yu-qian, Hu Cheng, Zhang Rong, Wang Cong-rong, Lu Jun-xi, Jia Wei-ping, Xiang Kun-san
Abstract excerpt
AIM: The aim of the present study was to investigate the relationship between R219K, M883I, and R1587K variants of the ATP-binding cassette transporter subfamily A number 1 (ABCA1) gene and response to rosiglitazone treatment in newly diagnosed patients with type 2 diabetes. METHODS: A total of 105 diabetic patients with no history of antihyperglycemia medication were treated with rosiglitazone (4 or 8 mg daily)...
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