Article
Adiponectin gene polymorphism rs2241766 T/G is associated with response to pioglitazone treatment in type 2 diabetic patients from southern China.
PloS one - 1 Jan 2014
Yang Hong, Ye Enling, Si Guangxin, Chen Liangmiao, Cai Lingqiao, Ye Chengfu, Zhang Chi, Lu Xuemian
Abstract excerpt
INTRODUCTION: Insulin sensitizing drugs such as pioglitazone are not uniformly treatment effective among individual type 2 diabetic patients. Here, the relationship of pioglitazone efficacy to single nucleotide polymorphisms (SNP) of the adiponectin gene, a critical gene directly regulated by the drug, was examined in a cohort of Chinese Han type 2 diabetic patients. METHODS: Eighty type 2 diabetic patients were...
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