Article
Allele and haplotype frequencies of HLA-A, B, C, DRB1 and DQB1 genes in polytransfused patients in ethnically diverse populations from Brazil.
International journal of immunogenetics - 1 Oct 2015
Rodrigues C, Macedo L C, Bruder A V, Quintero F d C, de Alencar J B, Sell A M, Visentainer J E L
Abstract excerpt
The red blood transfusion is a practice often used in patients with haematological and oncological diseases. However, the investigation of human leucocyte antigen (HLA) system frequency in these individuals is of great importance because multiple transfusions may lead to HLA alloimmunization. Brazil is a country that was colonized by many other ethnicities, leading to a mixed ethnicity and regionalized...
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