Article
Prevalence of JAK2 V617F mutation in Indian patients with chronic myeloproliferative disorders.
The Indian journal of medical research - 1 Oct 2010
Sazawal Sudha, Bajaj Jyoti, Chikkara Sunita, Jain Sonal, Bhargava Rahul, Mahapatra Manoranjan, Saxena Renu
Abstract excerpt
BACKGROUND & OBJECTIVES: The Janus-associated Kinase-2 mutation JAK2 V617F in chronic myeloproliferative disorders (CMPDs) has been described as a frequent genetic event in majority of patients with polycythemia vera (PV), essential thrombocythemia (ET) and idiopathic myelofibrosis (IMF). Its frequency varies in different populations but there are no data from India. We therefore, looked for JAK2 V617F mutation...
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