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Article

A high-throughput and sensitive method to measure Global DNA Methylation: Application in Lung Cancer

3 Aug 2008

Abstract excerpt

BACKGROUND: Genome-wide changes in DNA methylation are an epigenetic phenomenon that can lead to the development of disease. The study of global DNA methylation utilizes technology that requires both expensive equipment and highly specialized skill sets. METHODS: We have designed and developed an assay, CpGlobal, which is easy-to-use, does not utilize PCR, radioactivity and expensive equipment. CpGlobal utilizes...

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PMID: 18673580
DOI: 10.1186/1471-2407-8-222

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