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DNA methylation biomarkers in biological fluids for early detection of respiratory tract cancer

1 Jan 2012

Abstract excerpt

Cancers of the respiratory tract (lung and head and neck) share common aetiologies, risk factors and molecular characteristics. Epigenetic reprogramming is one of the hallmarks of cancer and DNA methylation is currently the best-studied form. There are a number of characteristics of DNA methylation, which seem advantageous in biomarker development. Early detection is still an unmet clinical care need, which...

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PMID: 23089700
DOI: 10.1515/cclm-2012-0124

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