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Enhancing the reliability and throughput of neurosphere culture on hydrogel microwell arrays.

Stem cells (Dayton, Ohio) - 1 Oct 2008

Cordey Myriam, Limacher Monika, Kobel Stefan, Taylor Verdon, Lutolf Matthias P

Abstract excerpt

The neurosphere assay is the standard retrospective assay to test the self-renewal capability and multipotency of neural stem cells (NSCs) in vitro. However, it has recently become clear that not all neurospheres are derived from a NSC and that on conventional cell culture substrates, neurosphere motility may cause frequent neurosphere "merging" [Nat Methods 2006;3:801-806; Stem Cells 2007;25:871-874]. Combining...

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PMID: 18669905
DOI: 10.1634/stemcells.2008-0498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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