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Article

Multiscale, hierarchically patterned topography for directing human neural stem cells into functional neurons.

ACS nano - 26 Aug 2014

Yang Kisuk, Jung Hyunjung, Lee Hak-Rae, Lee Jong Seung, Kim Su Ran, Song Ki Yeong, Cheong Eunji, Bang Joona, Im Sung Gap, Cho Seung-Woo

Abstract excerpt

Various biophysical and biochemical factors are important for determining the fate of neural stem cells (NSCs). Among biophysical signals, topographical stimulation by micro/nanopatterns has been applied to control NSC differentiation. In this study, we developed a hierarchically patterned substrate (HPS) platform that can synergistically enhance the differentiation of human NSCs (hNSCs) by simultaneously...

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PMID: 25050736
DOI: 10.1021/nn501182f

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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