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Article

Expression of the Helicobacter pylori adhesin SabA is controlled via phase variation and the ArsRS signal transduction system.

Microbiology (Reading, England) - 1 Aug 2008

Goodwin Andrew C, Weinberger Daniel M, Ford Christopher B, Nelson Jessica C, Snider Jonathan D, Hall Joshua D, Paules Catharine I, Peek Richard M, Forsyth Mark H

Abstract excerpt

Adaptation to the acidic microenvironment, and adherence to mucosal epithelium, are essential for persistent colonization of the human stomach by Helicobacter pylori. The expression of SabA, an adhesin implicated in the ability of H. pylori to adhere to the host gastric epithelium, can be modulated by phase variation via slipped-strand mispairing in repetitive nucleotide tracts located in both the promoter region...

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Share to Adhesins, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Bacterial

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Source

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Identifiers

PMID: 18667556
DOI: 10.1099/mic.0.2007/016055-0
PMCID: PMC2715451

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression of the Helicobacter pylori adhesin SabA is controlled via phase variation and the ArsRS signal transduction system.PMID 18667556Read ↗

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