Article
Histidine residue 94 is involved in pH sensing by histidine kinase ArsS of Helicobacter pylori.
PloS one - 7 Sept 2009
Müller Stefanie, Götz Monika, Beier Dagmar
Abstract excerpt
BACKGROUND: The ArsRS two-component system is the master regulator of acid adaptation in the human gastric pathogen Helicobacter pylori. Low pH is supposed to trigger the autophosphorylation of the histidine kinase ArsS and the subsequent transfer of the phosphoryl group to its cognate response regulator ArsR which then acts as an activator or repressor of pH-responsive genes. Orthologs of the ArsRS two-component...
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