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Article

Influence of oipA Phase Variation on Virulence Phenotypes Related to Type IV Secretion System in Helicobacter pylori.

Helicobacter - 1 Jan 2000

Lai Jing, Angulmaduwa Sacheera, Kim Myeong-A, Kim Aeryun, Tissera Kavinda, Cho Yong-Joon, Cha Jeong-Heon

Abstract excerpt

BACKGROUND: oipA, an outer membrane protein of Helicobacter pylori, is linked to IL-8 induction and gastric inflammation, but its role is debated due to inconsistent findings. This study aims to explore the role of oipA phase variation in modulating the virulence traits of H. pylori, a bacterium strongly associated with the development of gastric cancer. MATERIAL AND METHODS: American clinical isolate AH868...

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PMID: 39440915
DOI: 10.1111/hel.13140

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