Article
Polymorphisms of the acid sensing histidine kinase gene arsS in Helicobacter pylori populations from anatomically distinct gastric sites.
Microbial pathogenesis - 1 Jan 2000
Hallinger Daniel R, Romero-Gallo Judith, Peek Richard M, Forsyth Mark H
Abstract excerpt
Phase variation is frequently utilized by bacterial species to affect gene expression such that phenotypic variants are maintained within populations, ensuring survival as environmental or host conditions change. Unusual among Helicobacter pylori phase variable or contingency genes is arsS, encoding a sensory histidine kinase involved in the acid acclimation of the organism. The presence of a 3' homopolymeric...
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