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Article

Association of GNB3 gene with pulse pressure and clustering of risk factors for cardiovascular disease in Japanese.

Biochemical and biophysical research communications - 9 Apr 2004

Yamamoto Miyuki, Abe Michiko, Jin Jing Ji, Wu Zhihong, Tabara Yasuharu, Mogi Masaki, Kohara Katsuhiko, Miki Tetsuro, Nakura Jun

Abstract excerpt

Heterotrimeric guanine nucleotide-binding proteins (G proteins) mediate many pathways including the beta-adrenergic signaling pathway. The C825T polymorphism in the gene coding for the beta3 subunit of G proteins (GNB3) has been shown to be associated with several phenotypes such as hypertension, obesity, and diabetes mellitus comprising the metabolic syndrome. The GNB3 C825T polymorphism may therefore be...

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Identifiers

PMID: 15033462
DOI: 10.1016/j.bbrc.2004.02.113

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of GNB3 gene with pulse pressure and clustering of risk factors for cardiovascular disease in Japanese.PMID 15033462Read ↗

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Human G-protein beta3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure.Semantic proximity Read ↗

G-Protein β3-Subunit Gene C825T Polymorphism and Cardiovascular Risk: An Updated Review.Semantic proximity Read ↗

The C825T polymorphism of the G-protein β3 subunit gene and its association with hypertension and stroke: an updated meta-analysis.Semantic proximity Read ↗

Association between the G-protein β3 subunit C825T polymorphism with essential hypertension: a meta-analysis in Han Chinese population.Semantic proximity Read ↗

GNB3 C825T polymorphism and elevated blood pressure.Semantic proximity Read ↗

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