Article
Mutation in the beta3 subunit of Guanine nucleotide-binding protein (GNB3) gene is not associated with Type II diabetes mellitus risk: a case-control study of a North Indian population.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Dec 2017
Rizvi Saliha, Raza Syed Tasleem, Rahman Qamar, Mahdi Farzana, Zaidi Zeashan Haider, Zaidi Alina
Abstract excerpt
CONTEXT: Genetics play a major role in development and pathophysiology of Type 2 diabetes mellitus (T2DM). OBJECTIVE: To asses the association of Guanine nucleotide-binding protein (GNB3) (C825T) gene's polymorphism with T2DM. MATERIALS AND METHODS: A case-control study including 400 North Indians was performed using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) approach to analyze...
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