Article
Allelic and phenotypic spectrum of plasma triglycerides.
Biochimica et biophysica acta - 1 May 2012
Johansen Christopher T, Hegele Robert A
Abstract excerpt
The genetic underpinnings of both normal and pathological variation in plasma triglyceride (TG) concentration are relatively well understood compared to many other complex metabolic traits. For instance, genome-wide association studies (GWAS) have revealed 32 common variants that are associated with plasma TG concentrations in healthy epidemiologic populations. Furthermore, GWAS in clinically ascertained...
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