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CK2 and the Hallmarks of Cancer

16 Aug 2022

Abstract excerpt

Cancer is a leading cause of death worldwide. Casein kinase 2 (CK2) is commonly dysregulated in cancer, impacting diverse molecular pathways. CK2 is a highly conserved serine/threonine kinase, constitutively active and ubiquitously expressed in eukaryotes. With over 500 known substrates and being estimated to be responsible for up to 10% of the human phosphoproteome, it is of significant importance. A broad...

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PMID: 36009534
DOI: 10.3390/biomedicines10081987

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