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Article

Genotype distribution of estrogen receptor-alpha, catechol-O-methyltransferase, and cytochrome P450 17 gene polymorphisms in Caucasian women with uterine leiomyomas.

Fertility and sterility - 1 Feb 2006

Denschlag Dominik, Bentz Eva-Katrin, Hefler Lukas, Pietrowski Detlef, Zeillinger Robert, Tempfer Clemens, Tong Dan

Abstract excerpt

OBJECTIVE: To evaluate the association between the presence of uterine leiomyomas and three functional single nucleotide polymorphisms (SNPs) of the estrogen receptor alpha (ESR1), catechol-O-methyltransferase (COMT), and cytochrom P450 17 (CYP17A) genes, which have been described to modify the estrogen metabolism. DESIGN: Prospective case control study. SETTING: Academic research institution. PATIENT(S): One...

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Source

Identifiers

PMID: 16595228
DOI: 10.1016/j.fertnstert.2005.07.1308

Genes

COMT
ESR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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