Article
Association of estrogen and progesterone receptor gene polymorphisms and their respective hormones in uterine leiomyomas.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2016
Veronica M, Ali Altaf, Venkateshwari A, Mamata D, Nallari Pratibha
Abstract excerpt
The steroid hormones estradiol and progesterone play an important role in the pathophysiology of fibroids that occurs in 20-25 % of women in the reproductive age. Our study examines the risk imposed by estrogen and progesterone plasma levels in correlation with the ERβ (-13950T/C) and PGR (+331G/A) receptor gene polymorphisms. The study population included 296 individuals (146 UL cases and 150 female controls)....
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