Article
Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins.
Antimicrobial agents and chemotherapy - 1 Oct 2008
Arendrup Maiken Cavling, Perkhofer Susanne, Howard Susan J, Garcia-Effron Guillermo, Vishukumar Aimanianda, Perlin David, Lass-Flörl Cornelia
Abstract excerpt
Two clinical isolates of Aspergillus fumigatus, designated AT and DK, were recently obtained from patients failing caspofungin and itraconazole therapy, respectively. The isolates were tested by microdilution for susceptibility to itraconazole, voriconazole, posaconazole, ravuconazole, and caspofungin and by Etest for susceptibility to amphotericin B and caspofungin. Susceptibility testing documented that the DK...
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