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Article

Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5.

The Journal of clinical investigation - 1 May 2013

Shi Hao, Verma Mayank, Zhang Lei, Dong Chen, Flavell Richard A, Bennett Anton M

Abstract excerpt

Duchenne muscular dystrophy (DMD) is a degenerative skeletal muscle disease caused by mutations in dystrophin. The degree of functional deterioration in muscle stem cells determines the severity of DMD. The mitogen-activated protein kinases (MAPKs), which are inactivated by MAPK phosphatases (MKPs), represent a central signaling node in the regulation of muscle stem cell function. Here we show that the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23543058
DOI: 10.1172/JCI64375
PMCID: PMC3635719

Genes

DMD
DUSP10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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