Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure.

Carcinogenesis - 1 Aug 2008

Jin Quanri, Menter David G, Mao Li, Hong Waun Ki, Lee Ho-Young

Abstract excerpt

The inhibitor of apoptosis protein survivin is selectively expressed in tumor cells. The tobacco component nicotine increases the transcription of the survivin gene in non-small cell lung cancer cells. However, the role of survivin expression induced by tobacco component is not clear during lung...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchi
Share to Inhibitor of Apoptosis Proteins
Share to Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nicotiana

Share to Precancerous Conditions

Share to RNA, Neoplasm

Share to RNA, Small Interfering

Share to Survivin

Source

Open in PubMed Open full text

Identifiers

PMID: 18635526
DOI: 10.1093/carcin/bgm234
PMCID: PMC2516487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18635526-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure.PMID 18635526Read ↗

The clinical significance of splice variants and subcellular localisation of survivin in non-small cell lung cancersSemantic proximity Read ↗

Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma ProgressionSemantic proximity Read ↗

Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.Semantic proximity Read ↗

Downregulation of Stem-loop binding protein by nicotine <i>via</i> α7-nicotinic acetylcholine receptor and its role in nicotine-induced cell transformationSemantic proximity Read ↗

The Influence Dose of Nicotine Exposure on H520 Smoking-related Non-Small-Cell Lung Carcinoma Cell Growth and ToxicitySemantic proximity Read ↗

Lessons learned from cancer may help in the treatment of pulmonary hypertension.Semantic proximity Read ↗

Nicotine overrides DNA damage-induced G1/S restriction in lung cells.Semantic proximity Read ↗

Nicotine Stimulates Human Lung Cancer Cell Growth by Inducing Fibronectin ExpressionSemantic proximity Read ↗

Role of survivin in EGFR inhibitor-induced apoptosis in non-small cell lung cancers positive for EGFR mutations.Semantic proximity Read ↗

Survivin mRNA expression in blood as a predictor of the response to EGFR-tyrosine kinase inhibitors and prognosis in patients with non-small cell lung cancer.Semantic proximity Read ↗

Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53.Semantic proximity Read ↗

Role of survivin re-expression in the development and progression of non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.