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Article

Survivin expression in normal human bronchial epithelial cells: an early and critical step in tumorigenesis induced by tobacco exposure.

Carcinogenesis - 1 Aug 2008

Jin Quanri, Menter David G, Mao Li, Hong Waun Ki, Lee Ho-Young

Abstract excerpt

The inhibitor of apoptosis protein survivin is selectively expressed in tumor cells. The tobacco component nicotine increases the transcription of the survivin gene in non-small cell lung cancer cells. However, the role of survivin expression induced by tobacco component is not clear during lung carcinogenesis. We investigated the effects of the tobacco components nicotine and its related carcinogen...

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Identifiers

PMID: 18635526
DOI: 10.1093/carcin/bgm234
PMCID: PMC2516487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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