Nicotine Stimulates Human Lung Cancer Cell Growth by Inducing Fibronectin Expression

Abstract excerpt

The mechanisms by which tobacco promotes lung cancer remain incompletely understood. Herein, we report that nicotine, a major component of tobacco, promotes the proliferation of cultured non-small cell lung carcinoma (NSCLC) cells; this effect was most noticeable at 5 days. However, nicotine had no effect on apoptosis of NSCLC cells. In experiments designed to unveil the mechanisms for this effect, we found that...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Click Chemistry and Applications
• Share to Monoclonal and Polyclonal Antibodies Research
• Share to Nicotinic Acetylcholine Receptors Study