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Article

Positive selection at the receptor-binding site of haemagglutinin H5 in viral sequences derived from human tissues.

The Journal of general virology - 1 Aug 2008

Kongchanagul Alita, Suptawiwat Ornpreya, Kanrai Pumaree, Uiprasertkul Mongkol, Puthavathana Pilaipan, Auewarakul Prasert

Abstract excerpt

Highly pathogenic H5N1 avian influenza virus has spread through at least 45 countries in three continents. Despite the ability to infect and cause severe disease in humans, the virus cannot transmit efficiently from human to human. The lack of efficient transmission indicates the incompletion of the adaptation of the avian virus to the new host species. The required mutations for the complete adaptation and the...

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Share to Hemagglutinin Glycoproteins, Influenza Virus
Share to Influenza A Virus, H5N1 Subtype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Virus

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Source

Identifiers

PMID: 18632950
DOI: 10.1099/vir.0.2008/002469-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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