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[Single nucleotide c.645+32c>T substitution in the APC gene is a non-pathogenic polymorphism appearing in about 16% of the Czech population].

Casopis lekaru ceskych - 1 Jan 2008

Plevová P, Drobcinská L, Stekrová J, Silhánová E

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis is an autosomal dominant disease characterised by predisposition to colon polyposis and colorectal cancer and caused by germline mutations in the APC gene. The aim of the study was to establish the frequency of c.645+32C>T substitution in intron 5 of the...

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Identifiers

PMID: 18630182

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18630182-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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