Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Single nucleotide c.645+32c>T substitution in the APC gene is a non-pathogenic polymorphism appearing in about 16% of the Czech population].

Casopis lekaru ceskych - 1 Jan 2008

Plevová P, Drobcinská L, Stekrová J, Silhánová E

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis is an autosomal dominant disease characterised by predisposition to colon polyposis and colorectal cancer and caused by germline mutations in the APC gene. The aim of the study was to establish the frequency of c.645+32C>T substitution in intron 5 of the APC gene in patients with multiple colon polyposis and in the general population and to determine if this substitution...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli
Share to Czech Republic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to APC gene

Share to Genes, APC

Share to Genetics, Population

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 18630182

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Single nucleotide c.645+32c>T substitution in the APC gene is a non-pathogenic polymorphism appearing in about 16% of the Czech population].PMID 18630182Read ↗

Genetic and clinical characterisation of familial adenomatous polyposis: a population based study.Semantic proximity Read ↗

Novel mutations of the APC gene in familial adenomatous polyposis in Greek patients.Semantic proximity Read ↗

Polymorphisms in the adenomatous polyposis coli gene in Slovak families suspected of FAP.Semantic proximity Read ↗

APC germline mutations identified in Czech patients with familial adenomatous polyposis.Semantic proximity Read ↗

[Characteristics of APC gene mutations in colorectal tumors].Semantic proximity Read ↗

Recurrent APC Splice Variant c.835-8A>G in Patients With Unexplained Colorectal Polyposis Fulfilling the Colibactin Mutational Signature.Semantic proximity Read ↗

Mutation analysis of the adenomatous polyposis coli (APC) gene in northwest Spanish patients with familial adenomatous polyposis (FAP) and sporadic colorectal cancer.Semantic proximity Read ↗

Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a case-control study in Taiwan.Semantic proximity Read ↗

The most frequent APC mutations among Slovak familial adenomatous polyposis patients. Adenomatous polyposis coli.Semantic proximity Read ↗

The spectrum of the APC pathogenic mutations in Slovak FAP patients.Semantic proximity Read ↗

Somatic mutations of the first 14 exons of APC in hamartomatous polyps of the colon.Semantic proximity Read ↗

Somatic APC mosaicism: a frequent cause of familial adenomatous polyposis (FAP).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.