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Article

Genetic and clinical characterisation of familial adenomatous polyposis: a population based study.

Gut - 1 Jun 2002

Moisio A-L, Järvinen H, Peltomäki P

Abstract excerpt

BACKGROUND: Familial adenomatous polyposis (FAP) is a rare autosomal dominantly inherited disease predisposing to colon cancer and caused by germline mutations in the APC (adenomatous polyposis coli) gene. AIMS: We conducted a population based study to evaluate the prevalence and clinical implications of APC mutations among Finnish FAP kindreds. A possible founder effect in parallel with previous observations in...

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Source

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Identifiers

PMID: 12010888
DOI: 10.1136/gut.50.6.845
PMCID: PMC1773245

Genes

APC
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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