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Article

Somatic mutations of the first 14 exons of APC in hamartomatous polyps of the colon.

Human mutation - 1 Oct 1999

Kim J C, Roh S A, Kim H C, Yu C S, Lee D H, Ahn B Y, Kim K M, Yang S K, Kang G H, Beck N E, Bodmer W F

Abstract excerpt

Although hamartomatous or hyperplastic polyps are rarely accompanied by adenomatous or carcinomatous foci, the role of APC (MIM# 175100) mutations in these polyps is not clear. The neoplastic potential of these polyps was assessed with regard to somatic mutation of the first 14 exons of APC. DNA from 14 hamartomatous polyps (12 patients with juvenile polyp, JP; two patients with Peutz-Jeghers syndrome, PJS) and...

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Source

Identifiers

PMID: 10502830
DOI: 10.1002/(SICI)1098-1004(199910)14:4<351::AID-HUMU13>3.0.CO;2-M

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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