Article
Cervical and vulvar cancer risk in relation to the joint effects of cigarette smoking and genetic variation in interleukin 2.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2008
Hussain Shehnaz K, Madeleine Margaret M, Johnson Lisa G, Du Qin, Malkki Mari, Wilkerson Hui-Wen, Farin Federico M, Carter Joseph J, Galloway Denise A, Daling Janet R, Petersdorf Effie W, Schwartz Stephen M
Abstract excerpt
Cigarette smoking is an established cofactor to human papillomavirus (HPV) in the development of cervical and vulvar squamous cell carcinoma (SCC), and may influence risk through an immunosuppressive pathway. Genetic variation in interleukin 2 (IL2), associated in some studies with the inhibition...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.