Article
Genetic variation in the TLR and NF-κB pathways and cervical and vulvar cancer risk: a population-based case-control study.
International journal of cancer - 15 Jan 2014
Bodelon Clara, Madeleine Margaret M, Johnson Lisa G, Du Qin, Galloway Denise A, Malkki Mari, Petersdorf Effie W, Schwartz Stephen M
Abstract excerpt
Genital infection with the oncogenic human papillomavirus is the necessary cause of cervical cancer and of a large fraction of vulvar cancers. The toll-like receptor and the nuclear factor κB (NF-κB) signaling pathways have been implicated in inflammation, autoimmune disease and cancer, but whether common nucleotide variation in these pathways is associated with the risk of cervical and vulvar cancers has...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.