Article
Genetic variations of interleukin-1 and -6 genes and risk of cervical intraepithelial neoplasia.
Gynecologic oncology - 1 Jun 2011
Grimm Christoph, Watrowski Rafal, Baumühlner Konstantin, Natter Camilla, Tong Dan, Wolf Andrea, Zeillinger Robert, Leodolter Sepp, Reinthaller Alexander, Hefler Lukas
Abstract excerpt
OBJECTIVE: To evaluate the association between five interleukin-1 (IL-1) and -6 gene polymorphisms and risk of high grade cervical intraepithelial neoplasia (CIN 2-3). METHODS: This case-control study investigates five common IL-1 and IL-6 gene polymorphisms in 131 women with CIN 2-3 and 209 controls by pyrosequencing and polymerase chain reaction. Associations between gene polymorphisms and risk of CIN 2-3 are...
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