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Article

Trophoblastic invasion in vitro and in vivo: similarities and differences

8 Jul 2008

Abstract excerpt

BACKGROUND: The basic mechanisms of trophoblast invasion are not completely understood. This may be due to the lack of suitable in vitro models which enable experimental modulation of this complex process. In the present study, a three-dimensional co-culture model is used for comparing two factors considered to be implicated in the regulation of trophoblast invasion, the expression of HLA-G and apoptosis, in...

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PMID: 18621754
DOI: 10.1093/humrep/den198

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