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Interaction of human trophoblast cells with gland-like endometrial spheroids: a model system for trophoblast invasion

5 Feb 2015

Abstract excerpt

STUDY QUESTION: Do maternal endometrial epithelial cell (EEC) differentiation and polarity impact the invasive capacity of extravillous trophoblast (EVT) cells during early human implantation? SUMMARY ANSWER: In a three dimensional (3D) confrontation co-culture the invasiveness of the human trophoblast cell line AC-1M88 was inversely correlated with the degree of differentiation and polarization of human...

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PMID: 25662813
DOI: 10.1093/humrep/dev011

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