Article
Toll-like receptors 2 and 4 gene polymorphisms in a Chinese population with periodontitis.
Quintessence international (Berlin, Germany : 1985) - 1 Mar 2008
Zhu Guangxun, Li Chengzhang, Cao Zhengguo, Corbet Esmonde F, Jin Lijian
Abstract excerpt
OBJECTIVES: Polymorphisms for toll-like receptor (TLR) 2 gene (Arg677Trp, Arg753Gln) and TLR4 gene (Asp299Gly, Thr399Ile) that are associated with impaired lipopolysaccharide (LPS) signal transduction have recently been described. The present study aimed to investigate the relationship between TLRs 2 and 4 gene polymorphisms and periodontitis in a Chinese population. METHOD AND MATERIALS: Forty patients with...
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