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Article

Influence of cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphisms in periodontitis.

Archives of oral biology - 1 Sept 2012

Houshmand B, Rafiei A, Hajilooi M

Abstract excerpt

AIM: Persistent host inflammatory immune response against the pathogens results in the destruction of periodontal tissues. Cytotoxic T lymphocyte antigen 4 (CTLA-4) is a particularly important molecule in down-regulating T-cell expansion and cytokine production. This study aimed to assess three functional SNPs within CTLA-4 gene, -1722 T/C, -318 C/T, and +49 A/G in patients with aggressive or chronic...

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Source

Identifiers

PMID: 22497911
DOI: 10.1016/j.archoralbio.2012.03.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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