Article
Toll-like receptor 2 and 4 gene polymorphisms in generalized aggressive periodontitis.
Journal of periodontology - 1 Oct 2007
Emingil Gülnur, Berdeli Afig, Baylas Haluk, Saygan Buket Han, Gürkan Ali, Köse Timur, Atilla Gül
Abstract excerpt
BACKGROUND: Toll-like receptors (TLRs) recognize exogenous ligands such as lipopolysaccharide and bacterial lipoprotein during the immune responses to pathogens. The aim of the present study was to investigate whether TLR2 and TLR4 gene polymorphisms are related to susceptibility to generalized aggressive periodontitis (GAgP). METHODS: A total of 245 subjects were included in the present study. Genomic DNA was...
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