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Article

Polymorphism of genes encoding toll-like receptors and inflammatory cytokines in periodontal disease in the Japanese population.

Journal of the International Academy of Periodontology - 1 Jul 2008

Imamura Yasuhiro, Fujigaki Yoshihisa, Oomori Yuriko, Kuno Tomoko, Ota Norio, Wang Pao-Li

Abstract excerpt

Periodontitis, which is a widespread and major dental disease, is a multifactorial, lifestyle-related disease and has been analyzed for gene polymorphism. We examined the frequency of the polymorphisms of the pro-inflammatory cytokine genes IL-1 A (-889) and IL-1 B (+3953) in relation to periodontitis in the Japanese population. We also examined whether polymorphism of TLR2 (Arg677Trp) and TLR4 (Asp299Gly), which...

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PMID: 18714935

Genes

TLR2
TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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