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Article

Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.

PloS one - 9 Jul 2008

Chiang Y Jeffrey, Hsiao Susan J, Yver Dena, Cushman Samuel W, Tessarollo Lino, Smith Susan, Hodes Richard J

Abstract excerpt

Tankyrases are proteins with poly(ADP-ribose) polymerase activity. Human tankyrases post-translationally modify multiple proteins involved in processes including maintenance of telomere length, sister telomere association, and trafficking of glut4-containing vesicles. To date, however, little is known about in vivo functions for tankyrases. We recently reported that body size was significantly reduced in mice...

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Share to Embryo, Mammalian
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18612384
DOI: 10.1371/journal.pone.0002639
PMCID: PMC2441437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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