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Article

Recruitment and Endo-Lysosomal Activation of TLR9 in Dendritic Cells Infected with <i>Trypanosoma cruzi</i>

1 Jul 2008

Abstract excerpt

TLR9 is critical in parasite recognition and host resistance to experimental infection with Trypanosoma cruzi. However, no information is available regarding nucleotide sequences and cellular events involved on T. cruzi recognition by TLR9. In silico wide analysis associated with in vitro screening of synthetic oligonucleotides demonstrates that the retrotransposon VIPER elements and mucin-like glycoprotein...

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PMID: 18606688
DOI: 10.4049/jimmunol.181.2.1333

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