Article

Recognition of <i>Chlamydia trachomatis</i> by Toll-Like Receptor 9 is altered during persistence

2024-02-08

Abstract excerpt

<h4>ABSTRACT</h4> Toll-like receptor 9 (TLR9) is an innate immune receptor that localizes to endosomes in antigen presenting cells and recognizes single stranded unmethylated CpG sites on bacterial genomic DNA. Previous bioinformatic studies have indicated that the genome of the human pathogen Chlamydia trachomatis contains TLR9 stimulatory motifs, and correlative studies have implied a link between human TLR9 (...

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Literature Corpus work: a05e5e37-0696-561e-bf3b-72778bdae56a
DOI: 10.1101/2024.02.06.579186

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