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Article

Morphogenetic differences between fore and hind limb precartilage mesenchyme: relation to mechanisms of skeletal pattern formation.

Developmental biology - 1 Mar 1994

Downie S A, Newman S A

Abstract excerpt

Using a serum-free culture system, we have investigated morphogenetic differences between fore and hind limb precartilage mesenchymal cells derived from stages 21-26 chicken embryos. Across all stages, wing and leg cultures were intrinsically different in the amount and spatial organization of cartilage that they produced. By stage 24, leg cells began to produce a nodular pattern of cartilage while wing cells...

Topics

Animals
Cartilage
Cells, Cultured
Chick Embryo
Culture Media
Fibronectins
Hindlimb
Mesoderm
Morphogenesis
Phenotype
Proteoglycans
Transforming Growth Factor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tretinoin

Wings, Animal

Source

Identifiers

PMID: 8125187
DOI: 10.1006/dbio.1994.1078

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8125187-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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