Article
Assessment of genetic risk factors for thoracic aortic aneurysm in hypertensive patients.
American journal of hypertension - 1 Sept 2008
Kato Kimihiko, Oguri Mitsutoshi, Kato Noriyuki, Hibino Takeshi, Yajima Kazuhiro, Yoshida Tetsuro, Metoki Norifumi, Yoshida Hidemi, Satoh Kei, Watanabe Sachiro, Yokoi Kiyoshi, Murohara Toyoaki, Yamada Yoshiji
Abstract excerpt
BACKGROUND: Conventional risk factors for thoracic aortic aneurysm including dissection (TAA) are thought to include age, arteriosclerosis, and hypertension. In addition, evidence suggests that genetic factors play a role in the development of this condition. The purpose of the present study was to identify genetic variants that confer susceptibility to TAA in hypertensive subjects. METHODS: Study subjects...
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