Article
Deletion of the msdS/AfmsdC gene induces abnormal polarity and septation in Aspergillus fumigatus.
Microbiology (Reading, England) - 1 Jul 2008
Li Yanjie, Zhang Lei, Wang Depeng, Zhou Hui, Ouyang Haomiao, Ming Jia, Jin Cheng
Abstract excerpt
alpha-Mannosidases play an important role in the processing of mannose-containing glycans in eukaryotes. A deficiency in alpha-mannosidase is lethal in humans and cattle. In contrast to mammals, Saccharomyces cerevisiae does not require the endoplasmic reticulum alpha-mannosidase gene for growth. However, little is known of the consequence of loss of function of class I alpha-mannosidases in filamentous fungi. In...
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