Article
N-Glycosylation of Gel1 or Gel2 is vital for cell wall β-glucan synthesis in Aspergillus fumigatus.
Glycobiology - 1 Aug 2013
Zhao Wan, Lü Yang, Ouyang Haomiao, Zhou Hui, Yan Jianghong, Du Ting, Jin Cheng
Abstract excerpt
Fungal cell wall is a dynamic structure that communicates with and protects the cell from outside stress. In Aspergillus fumigatus, the cell wall β-glucans are mainly elongated by β-1,3-glucanosyltransferases Gels, which consist of seven family members (Gel1-7) utilizing β-1,3-glucan chains as substrates. Previously, we have shown that the mutant deficient of N-glycan processing displays a reduction in the cell...
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